| Gene Information | |
|---|---|
| Gene Name | NUP54 |
| Organism | Homo sapiens (Human) |
| Gene Length | 507 |
| Protein Names | Nucleoporin p54 (54 kDa nucleoporin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000138750 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7Z3B4 |
| Gene Card | NUP54 |
| Uniprot ID | Q7Z3B4 |
| Pfam | PF13874; PF18437 |
| In ASD | no |
| Allosteric Prediction | no (-0.368324846) |
| Ortholog in Animals | Alpaca_ NUP54 ( ortholog_one2one ) Dog_ NUP54 ( ortholog_one2one ) GuineaPig_ NUP54 ( ortholog_one2one ) Macaque_ NUP54 ( ortholog_one2one ) Mouse_ Nup54 ( ortholog_one2one ) Pig_ NUP54 ( ortholog_one2one ) Rat_ Nup54 ( ortholog_one2one ) Rabbit_ NUP54 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001759(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4JNU (X-ray 1.44A ) 4JNV (X-ray 1.85A ) 4JO7 (X-ray 1.75A ) 4JO9 (X-ray 2.50A ) 5IJN (EM 21.40A ) 5IJO (EM 21.40A ) 7N8R (X-ray 1.20A ) 7PER (EM 35.00A ) 7R5K (EM 12.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:P70582}. Nucleus membrane {ECO:0000250|UniProtKB:P70582}; Peripheral membrane protein {ECO:0000250|UniProtKB:P70582}; Cytoplasmic side {ECO:0000250|UniProtKB:P70582}. Nucleus membrane {ECO:0000250|UniProtKB:P70582}; Peripheral membrane protein {ECO:0000250|UniProtKB:P70582}; Nucleoplasmic side {ECO:0000250|UniProtKB:P70582}. Note=Biased towards cytoplasmic side. Central region of the nuclear pore complex, within the transporter. {ECO:0000250|UniProtKB:P70582}. |
| Mouse PG classification | NA |
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