| Gene Information | |
|---|---|
| Gene Name | NUP42 |
| Organism | Homo sapiens (Human) |
| Gene Length | 423 |
| Protein Names | Nucleoporin NUP42 (NLP-1) (NUP42 homolog) (Nucleoporin hCG1) (Nucleoporin-42) (Nucleoporin-like protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000136243 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O15504 |
| Gene Card | NUP42 |
| Uniprot ID | O15504 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.204632894) |
| Ortholog in Animals | Alpaca_ NUP42 ( ortholog_one2one ) Dog_ NUP42 ( ortholog_one2one ) GuineaPig_ NUP42 ( ortholog_one2one ) Macaque_ NUP42 ( ortholog_one2one ) Mouse_ Nupl2 ( ortholog_one2one ) Pig_ NUP42 ( ortholog_one2one ) Rat_ Nupl2 ( ortholog_one2one ) Rabbit_ NUP42 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LENG9 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:10358091}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002419(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6B4F (X-ray 2.81A ) 6B4I (X-ray 3.62A ) 6B4J (X-ray 3.40A ) |
| DBSNP | rs13243961 rs34902971 |
| Subcellular location [CC] | Nucleus, nuclear pore complex {ECO:0000269|PubMed:12228227, ECO:0000269|PubMed:16000379}. Nucleus membrane {ECO:0000269|PubMed:12228227, ECO:0000269|PubMed:16000379}; Peripheral membrane protein; Cytoplasmic side {ECO:0000269|PubMed:12228227}. Note=Excluded from the nucleolus. {ECO:0000269|PubMed:10358091}. |
| Mouse PG classification | NA |
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