| Gene Information | |
|---|---|
| Gene Name | NUDT7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 238 |
| Protein Names | Peroxisomal coenzyme A diphosphatase NUDT7 (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 7) (Nudix motif 7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000140876 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P0C024 |
| Gene Card | NUDT7 |
| Uniprot ID | P0C024 |
| Pfam | PF00293 |
| In ASD | no |
| Allosteric Prediction | no (-0.438392554) |
| Ortholog in Animals | Alpaca_ NUDT7 ( ortholog_one2one ) Dog_ NUDT7 ( ortholog_one2one ) GuineaPig_ NUDT7 ( ortholog_one2one ) Macaque_ NUDT7 ( ortholog_one2one ) Mouse_ Nudt7 ( ortholog_one2one ) Pig_ NUDT7 ( ortholog_one2one ) Rat_ Nudt7 ( ortholog_one2one ) Rabbit_ NUDT7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in liver, kidney, pancreas, pituitary, small intestine, spleen, heart and placenta. Weakly expressed in brain. {ECO:0000269|PubMed:11415433}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 5QGG (X-ray 1.91A ) 5QGH (X-ray 1.82A ) 5QGI (X-ray 1.95A ) 5QGJ (X-ray 1.95A ) 5QGK (X-ray 1.81A ) 5QGL (X-ray 2.27A ) 5QGM (X-ray 1.96A ) 5QGN (X-ray 1.95A ) 5QGO (X-ray 1.82A ) 5QGP (X-ray 2.09A ) 5QGQ (X-ray 1.95A ) 5QGR (X-ray 1.96A ) 5QGS (X-ray 1.55A ) 5QGT (X-ray 1.97A ) 5QGU (X-ray 1.71A ) 5QGV (X-ray 1.59A ) 5QGW (X-ray 1.94A ) 5QGX (X-ray 1.61A ) 5QGY (X-ray 1.72A ) 5QGZ (X-ray 1.65A ) 5QH0 (X-ray 1.57A ) 5QH1 (X-ray 1.65A ) 5QH2 (X-ray 1.74A ) 5QH3 (X-ray 1.65A ) 5QH4 (X-ray 1.67A ) 5QH5 (X-ray 1.85A ) 5QH6 (X-ray 2.00A ) 5QH7 (X-ray 1.74A ) 5QH8 (X-ray 1.75A ) 5QH9 (X-ray 1.72A ) 5QHA (X-ray 1.57A ) 5QHB (X-ray 1.57A ) 5QHC (X-ray 2.21A ) 5QHE (X-ray 1.74A ) 5QHF (X-ray 1.67A ) 5QHG (X-ray 1.92A ) 5QHH (X-ray 1.52A ) 5T3P (X-ray 2.03A ) |
| DBSNP | rs308925 rs16946429 |
| Subcellular location [CC] | Peroxisome {ECO:0000250|UniProtKB:Q99P30}. |
| Mouse PG classification | NA |
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