Gene Information
Gene NameNUDT11
OrganismHomo sapiens (Human)
Gene Length164
Protein NamesDiphosphoinositol polyphosphate phosphohydrolase 3-beta (DIPP-3-beta) (DIPP3-beta) (hDIPP3beta) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta) (Diadenosine hexaphosphate hydrolase (AMP-forming)) (EC 3.6.1.60) (Nucleoside diphosphate-linked moiety X motif 11) (Nudix motif 11) (hAps1)
Target NameNA
Target TypeNA
Gene Age101 ( ENSG00000196368 )
Evolutionary StageEukaryota
AlphaFoldDBQ96G61
Gene CardNUDT11
Uniprot IDQ96G61
PfamPF00293
In ASDno
Allosteric Predictionno (-1.196507838)
Ortholog in AnimalsDog_ NUDT11 ( ortholog_one2many )
Macaque_ NUDT11 ( ortholog_one2one )
Mouse_ Nudt11 ( ortholog_one2many )
Mouse_ Nudt10 ( ortholog_one2many )
Rat_ Nudt10 ( ortholog_one2one )
Rabbit_ NUDT11 ( ortholog_one2one )
OhnologsNA
ParalogsNUDT3, NUDT10, NUDT4, NUDT4B
Tissuebrain, testis, cerebral.cortex
Tissue SpecificityMainly expressed in testis and, at lower level in brain. According to PubMed:12121577, it is also expressed in pancreas and weakly expressed in thymus, prostate, ovary, lung, small intestine and heart. {ECO:0000269|PubMed:12105228, ECO:0000269|PubMed:12121577}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:12121577}.
Mouse PG classificationNA
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