| Gene Information | |
|---|---|
| Gene Name | RNF220 |
| Organism | Homo sapiens (Human) |
| Gene Length | 566 |
| Protein Names | E3 ubiquitin-protein ligase RNF220 (EC 2.3.2.27) (RING finger protein 220) (RING-type E3 ubiquitin transferase RNF220) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000187147 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q5VTB9 |
| Gene Card | RNF220 |
| Uniprot ID | Q5VTB9 |
| Pfam | PF15926 |
| In ASD | no |
| Allosteric Prediction | no (-0.813324159) |
| Ortholog in Animals | Alpaca_ RNF220 ( ortholog_one2one ) GuineaPig_ RNF220 ( ortholog_one2one ) Macaque_ RNF220 ( ortholog_one2one ) Mouse_ Rnf220 ( ortholog_one2one ) Pig_ RNF220 ( ortholog_one2one ) Rat_ Rnf220 ( ortholog_one2one ) Rabbit_ RNF220 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Abundant in brain and spinal cord, particularly in the cerebellum and cerebral cortex. In fetal tissues expressed in the cerebellum, spinal cord and cortex. {ECO:0000269|PubMed:33964137}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:33964137}. Nucleus {ECO:0000269|PubMed:33964137}. |
| Mouse PG classification | NA |
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