| Gene Information | |
|---|---|
| Gene Name | NUBP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 271 |
| Protein Names | Cytosolic Fe-S cluster assembly factor NUBP2 (Nucleotide-binding protein 2) (NBP 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000095906 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9Y5Y2 |
| Gene Card | NUBP2 |
| Uniprot ID | Q9Y5Y2 |
| Pfam | PF10609 |
| In ASD | no |
| Allosteric Prediction | no (-0.893898356) |
| Ortholog in Animals | Alpaca_ NUBP2 ( ortholog_one2one ) Dog_ NUBP2 ( ortholog_one2one ) GuineaPig_ NUBP2 ( ortholog_one2one ) Macaque_ NUBP2 ( ortholog_one2one ) Mouse_ Nubp2 ( ortholog_one2one ) Pig_ NUBP2 ( ortholog_one2one ) Rat_ Nubp2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NUBP1, NUBPL |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest expression in skeletal muscle. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs57822546 rs35030308 rs34028164 |
| Subcellular location [CC] | Nucleus {ECO:0000255|HAMAP-Rule:MF_03039}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000255|HAMAP-Rule:MF_03039}. Cytoplasm {ECO:0000269|PubMed:29848660}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q9R061}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q9R061}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:Q9R061}. Note=Enriched at the centrosomes during mitosis. Enriched in centrioles of microtubule asters during prophase, prometaphase and telophase stages of mitosis (By similarity). Localized at centrioles and in the nucleus at interphase (By similarity). Colocalizes with nubp-1 at prometaphase (By similarity). {ECO:0000250|UniProtKB:Q9R061, ECO:0000255|HAMAP-Rule:MF_03039}. |
| Mouse PG classification | NA |
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