Gene Information
Gene NameNUBP1
OrganismHomo sapiens (Human)
Gene Length320
Protein NamesCytosolic Fe-S cluster assembly factor NUBP1 (Nucleotide-binding protein 1) (NBP 1)
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000103274 )
Evolutionary StageCellular_organisms
AlphaFoldDBP53384
Gene CardNUBP1
Uniprot IDP53384
PfamPF10609
In ASDno
Allosteric Predictionno (-0.931901795)
Ortholog in AnimalsAlpaca_ NUBP1 ( ortholog_one2one )
Dog_ NUBP1 ( ortholog_one2one )
GuineaPig_ NUBP1 ( ortholog_one2one )
Macaque_ NUBP1 ( ortholog_one2one )
Mouse_ Nubp1 ( ortholog_one2one )
Pig_ NUBP1 ( ortholog_one2one )
Rabbit_ NUBP1 ( ortholog_one2one )
OhnologsNA
ParalogsNUBPL, NUBP2
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2233531 
Subcellular location [CC]Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03038, ECO:0000269|PubMed:18573874, ECO:0000269|PubMed:29848660}. Nucleus {ECO:0000250|UniProtKB:Q9R060}. Cell projection {ECO:0000250|UniProtKB:Q9R060}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q9R060}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q9R060}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:Q9R060}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q9R060}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Enriched in centrioles of microtubule asters during prophase, prometaphase and telophase stages of mitosis. Localized at centrioles and in the nucleus at interphase. Colocalizes with nubp-2 at prometaphase. Specifically localizes to the axenome of motile cilia as opposed to primary non-motile cilia. Localization is independent of NUBP2 and KIFC1. {ECO:0000250|UniProtKB:Q9R060}.
Mouse PG classificationNA
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