| Gene Information | |
|---|---|
| Gene Name | NTRR |
| Organism | Homo sapiens (Human) |
| Gene Length | 418 |
| Protein Names | Neurotensin receptor type 1 (NT-R-1) (NTR1) (High-affinity levocabastine-insensitive neurotensin receptor) (NTRH) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P30989 |
| Gene Card | NTSR1 |
| Uniprot ID | P30989 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain. {ECO:0000269|PubMed:20048080, ECO:0000269|PubMed:8381365}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.002990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LYW (NMR - ) 6OS9 (EM 3.00A ) 6OSA (EM 3.00A ) 6PWC (EM 4.90A ) 6UP7 (EM 4.20A ) 7UL2 (EM 2.40A ) |
| DBSNP | rs11698783 rs35373650 rs2273075 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:8381365}; Multi-pass membrane protein {ECO:0000305}. Membrane raft {ECO:0000269|PubMed:21725197}. Note=Palmitoylation is required for localization at CAV1-enriched membrane rafts. {ECO:0000269|PubMed:21725197}. |
| Mouse PG classification | NA |
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