Gene Information
Gene NameNTN4
OrganismHomo sapiens (Human)
Gene Length628
Protein NamesNetrin-4 (Beta-netrin) (Hepar-derived netrin-like protein)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000074527 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9HB63
Gene CardNTN4
Uniprot IDQ9HB63
PfamPF00053; PF00055; PF01759
In ASDno
Allosteric Predictionno (-1.194686159)
Ortholog in AnimalsAlpaca_ NTN4 ( ortholog_one2one )
Dog_ NTN4 ( ortholog_one2one )
GuineaPig_ NTN4 ( ortholog_one2one )
Macaque_ NTN4 ( ortholog_one2one )
Mouse_ Ntn4 ( ortholog_one2one )
Pig_ NTN4 ( ortholog_one2one )
Rat_ Ntn4 ( ortholog_one2one )
Rabbit_ NTN4 ( ortholog_one2one )
OhnologsNA
ParalogsLAMB2, LAMC3, LAMB1, LAMA3, LAMC1, ATRNL1, LAMA2, TMEFF2, ATRN, NTN1, NTN3, LAMC2, TMEFF1, LAMA1, AGRN, LAMB4, NTNG2, NTNG1, LAMA4, MEGF9, MEGF8, LAMB3, EGFLAM, LAMA5, NTN5, USH2A, HSPG2
TissueNA
Tissue SpecificityExpressed in kidney, spleen, mammary gland, aorta, heart, ovary, prostate and fetal spleen. {ECO:0000269|PubMed:11038171}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17288108 
Subcellular location [CC]Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000269|PubMed:11038171}. Note=Major component.
Mouse PG classificationNA
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