| Gene Information | |
|---|---|
| Gene Name | NTN1L |
| Organism | Homo sapiens (Human) |
| Gene Length | 604 |
| Protein Names | Netrin-1 (Epididymis tissue protein Li 131P) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O95631 |
| Gene Card | NTN1 |
| Uniprot ID | O95631 |
| Pfam | PF00053; PF00055; PF01759 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas. Expressed in epididymis (at protein level). {ECO:0000269|PubMed:20736409, ECO:0000269|PubMed:9950216}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);0.046154(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4URT (X-ray 3.10A ) 6FKQ (X-ray 3.07A ) 7NDG (EM 5.98A ) 7NE0 (X-ray 3.25A ) 7NE1 (X-ray 3.15A ) |
| DBSNP | rs531668666 rs1567749982 rs1567750186 rs1567750187 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:28945198}. Cytoplasm {ECO:0000269|PubMed:28945198}. Note=Mainly secreted. {ECO:0000269|PubMed:28945198}. |
| Mouse PG classification | NA |
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