| Gene Information | |
|---|---|
| Gene Name | NTF4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 210 |
| Protein Names | Neurotrophin-4 (NT-4) (Neurotrophin-5) (NT-5) (Neutrophic factor 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000225950 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P34130 |
| Gene Card | NTF4 |
| Uniprot ID | P34130 |
| Pfam | PF00243 |
| In ASD | no |
| Allosteric Prediction | no (-0.161690653) |
| Ortholog in Animals | Alpaca_ NTF4 ( ortholog_one2one ) Dog_ NTF4 ( ortholog_one2one ) GuineaPig_ NTF4 ( ortholog_one2one ) Macaque_ NTF4 ( ortholog_one2one ) Mouse_ Ntf5 ( ortholog_one2one ) Pig_ NTF4 ( ortholog_one2one ) Rat_ Ntf4 ( ortholog_one2one ) Rabbit_ NTF4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BDNF, NGF, NTF3 |
| Tissue | NA |
| Tissue Specificity | Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1B8M (X-ray 2.75A ) 1B98 (X-ray 2.75A ) 1HCF (X-ray 2.70A ) |
| DBSNP | rs756962734 rs61732310 rs374367338 rs751743400 rs766504681 rs377553005 rs977260366 rs201069064 rs121918428 rs121918427 rs371861346 rs200675509 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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