Gene Information
Gene NameNTE
OrganismHomo sapiens (Human)
Gene Length1375
Protein NamesPatatin-like phospholipase domain-containing protein 6 (EC 3.1.1.5) (Neuropathy target esterase)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ8IY17
Gene CardPNPLA6
Uniprot IDQ8IY17
PfamPF00027; PF01734
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in brain, placenta, kidney, neuron and skeletal muscle. Expressed in the developing eye, pituitary and brain. {ECO:0000269|PubMed:25480986, ECO:0000269|PubMed:9576844}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs587777184  rs17854645  rs587777615  rs587777185  rs121434416  rs17854647  rs541098659  rs587777181  rs121434415  rs587777183  rs786201037  rs754429587  rs587777182  rs748506175  rs773955314  rs587777854  rs1555751592  rs142422525  rs1211079280  rs374434303  rs1204274988 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000269|PubMed:15044461};
Single-pass type III membrane protein {ECO:0000269|PubMed:15044461}.
Mouse PG classificationNA
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