| Gene Information | |
|---|---|
| Gene Name | NTCP |
| Organism | Homo sapiens (Human) |
| Gene Length | 349 |
| Protein Names | Hepatic sodium/bile acid cotransporter (Cell growth-inhibiting gene 29 protein) (Na(+)/bile acid cotransporter) (Na(+)/taurocholate transport protein) (Sodium/taurocholate cotransporting polypeptide) (NTCP) (Solute carrier family 10 member 1) (SLC10A1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q14973 |
| Gene Card | SLC10A1 |
| Uniprot ID | Q14973 |
| Pfam | PF01758 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in liver (PubMed:11031103, PubMed:12409283). Expressed in placental trophoblasts (PubMed:12409283). {ECO:0000269|PubMed:11031103, ECO:0000269|PubMed:12409283, ECO:0000269|PubMed:9458785}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7FCI (EM 3.30A ) 7PQG (EM 3.70A ) 7PQQ (EM 3.30A ) 7VAD (EM 3.41A ) 7VAG (EM 3.32A ) 7WSI (EM 3.32A ) 7ZYI (EM 2.88A ) |
| DBSNP | rs200758433 rs536458730 rs111885789 rs202018997 rs763683476 rs148467625 rs543063679 rs144006534 rs571796903 rs553948182 rs746174545 rs61745930 rs190268737 rs139931299 rs150579813 rs76966244 rs141269120 rs147226818 rs141269120 rs541801766 rs2296651 rs72547507 rs189313778 rs72547506 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:14660639, ECO:0000269|PubMed:24867799}; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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