| Gene Information | |
|---|---|
| Gene Name | ACTA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 377 |
| Protein Names | Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form] |
| Target Name | actin, aortic smooth muscle |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000107796 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P62736 |
| Gene Card | ACTA2 |
| Uniprot ID | P62736 |
| Pfam | PF00022 |
| In ASD | no |
| Allosteric Prediction | yes (0.200467962) |
| Ortholog in Animals | Alpaca_ ACTA2 ( ortholog_one2one ) Dog_ ACTA2 ( ortholog_one2one ) GuineaPig_ ACTA2 ( ortholog_one2one ) Macaque_ ACTA2 ( ortholog_one2one ) Mouse_ Acta2 ( ortholog_one2one ) Pig_ ACTA2 ( ortholog_one2one ) Rat_ Acta2 ( ortholog_one2one ) Rabbit_ ACTA2 ( ortholog_one2one ) |
| Ohnologs | ACTC1, ACTA1, ACTG2 |
| Paralogs | ACTG2, ACTC1, ACTBL2, ACTR1A, ACTB, ACTG1, ACTR5, ACTL9, ACTR3, ACTL7A, ACTL7B, ACTL8, ACTA1, ACTL6B, ACTR3B, ACTR3C, ACTRT2, ACTR8, ACTR1B, ACTL6A, ACTR2, ACTR6, ACTRT1, ACTRT3, ACTL10, ACTR10 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs794728021 rs112602953 rs751300489 rs121434526 rs1554841298 rs387906592 rs1057521105 rs1803028 rs397516685 rs121434528 rs121434527 rs1803027 rs777832794 rs1062398 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton. |
| Mouse PG classification | HPG |
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