| Gene Information | |
|---|---|
| Gene Name | POU5F1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 359 |
| Protein Names | Putative POU domain, class 5, transcription factor 1B (Oct4-pg1) (Octamer-binding protein 3-like) (Octamer-binding transcription factor 3-like) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000212993 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q06416 |
| Gene Card | POU5F1B |
| Uniprot ID | Q06416 |
| Pfam | PF00046; PF00157 |
| In ASD | no |
| Allosteric Prediction | no (-1.252355481) |
| Ortholog in Animals | Alpaca_ POU5F1B ( ortholog_one2one ) Mouse_ Pou5f1 ( ortholog_one2many ) Rat_ Pou5f1 ( ortholog_one2many ) Rabbit_ POU5F1 ( ortholog_one2many ) |
| Ohnologs | POU3F2, POU3F1 |
| Paralogs | POU1F1, POU2F3, POU4F3, POU3F3, POU6F1, POU4F1, CCDC160, HDX, POU2F1, POU3F1, POU5F2, POU4F2, POU6F2, POU2F2, POU3F2, POU3F4, POU5F1 |
| Tissue | NA |
| Tissue Specificity | Detected at the mRNA level in several cancer tissues (breast, uterine cervix, lung, thyroid gland, esophagus, colon, urinary bladder, and glioma), but absent in normal tissues. {ECO:0000269|PubMed:16229821, ECO:0000269|PubMed:21341266}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004800(Rat);0.047826(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1061394 rs1061395 rs6998061 rs13273814 rs13274084 rs7002225 rs556361752 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00530, ECO:0000269|PubMed:18949397}. |
| Mouse PG classification | NA |
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