| Gene Information | |
|---|---|
| Gene Name | NT5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 574 |
| Protein Names | 5'-nucleotidase (5'-NT) (EC 3.1.3.35) (EC 3.1.3.5) (EC 3.1.3.89) (EC 3.1.3.91) (EC 3.1.3.99) (5'-deoxynucleotidase) (Ecto-5'-nucleotidase) (IMP-specific 5'-nucleotidase) (Thymidylate 5'-phosphatase) (CD antigen CD73) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P21589 |
| Gene Card | NT5E |
| Uniprot ID | P21589 |
| Pfam | PF02872; PF00149 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 4H1S (X-ray 2.20A ) 4H1Y (X-ray 1.58A ) 4H2B (X-ray 1.70A ) 4H2F (X-ray 1.85A ) 4H2G (X-ray 1.55A ) 4H2I (X-ray 2.00A ) 6HXW (X-ray 2.78A ) 6S7F (X-ray 2.05A ) 6S7H (X-ray 1.85A ) 6TVE (X-ray 1.05A ) 6TVG (X-ray 1.48A ) 6TVX (X-ray 2.60A ) 6TW0 (X-ray 2.50A ) 6TWA (X-ray 2.00A ) 6TWF (X-ray 2.50A ) 6VC9 (X-ray 2.25A ) 6VCA (X-ray 3.73A ) 6XUE (X-ray 1.94A ) 6XUG (X-ray 2.09A ) 6XUQ (X-ray 1.97A ) 6YE1 (X-ray 2.66A ) 6YE2 (X-ray 2.44A ) 6Z9B (X-ray 2.17A ) 6Z9D (X-ray 1.90A ) 7BBJ (X-ray 2.72A ) 7JV8 (X-ray 2.46A ) 7JV9 (X-ray 2.70A ) 7P9N (X-ray 1.55A ) 7P9R (X-ray 1.41A ) 7P9T (X-ray 1.79A ) 7PA4 (X-ray 1.45A ) 7PB5 (X-ray 1.28A ) 7PBA (X-ray 1.42A ) 7PBB (X-ray 1.47A ) 7PBY (X-ray 1.13A ) 7PCP (X-ray 1.38A ) 7PD9 (X-ray 1.39A ) 7QGA (X-ray 1.50A ) 7QGL (X-ray 1.50A ) 7QGM (X-ray 2.90A ) 7QGO (X-ray 2.21A ) |
| DBSNP | rs387906620 rs2229523 rs2229524 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:2129526, ECO:0000269|PubMed:24887587}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:2129526}. |
| Mouse PG classification | NA |
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