| Gene Information | |
|---|---|
| Gene Name | USP46 |
| Organism | Homo sapiens (Human) |
| Gene Length | 366 |
| Protein Names | Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000109189 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P62068 |
| Gene Card | USP46 |
| Uniprot ID | P62068 |
| Pfam | PF00443 |
| In ASD | no |
| Allosteric Prediction | yes (0.239367165) |
| Ortholog in Animals | Alpaca_ USP46 ( ortholog_one2one ) Dog_ USP46 ( ortholog_one2one ) GuineaPig_ USP46 ( ortholog_one2one ) Macaque_ USP46 ( ortholog_one2one ) Mouse_ Usp46 ( ortholog_one2one ) Pig_ USP46 ( ortholog_one2one ) Rat_ Usp46 ( ortholog_one2one ) Rabbit_ USP46 ( ortholog_one2one ) |
| Ohnologs | USP12 |
| Paralogs | USP12, USP39 |
| Tissue | NA |
| Tissue Specificity | Broadly expressed. {ECO:0000269|PubMed:14715245}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5CVM (X-ray 1.90A ) 5CVN (X-ray 3.36A ) 5CVO (X-ray 3.88A ) 5L8H (X-ray 1.85A ) 6JLQ (X-ray 3.10A ) |
| DBSNP | rs17475800 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
| click here to return to the previous page | |