| Gene Information | |
|---|---|
| Gene Name | NSP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 825 |
| Protein Names | Breast cancer anti-estrogen resistance protein 3 (Novel SH2-containing protein 2) (SH2 domain-containing protein 3B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O75815 |
| Gene Card | BCAR3 |
| Uniprot ID | O75815 |
| Pfam | PF00617; PF00017 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Found in several cancer cell lines, but not in nonmalignant breast tissue. {ECO:0000269|PubMed:10187783, ECO:0000269|PubMed:9582273}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3T6A (X-ray 2.40A ) |
| DBSNP | rs12062278 rs17110107 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q9QZK2}. Cell junction, focal adhesion {ECO:0000250|UniProtKB:Q9QZK2}. Note=Localization to focal adhesions depends on interaction with PTPRA. {ECO:0000250|UniProtKB:Q9QZK2}. |
| Mouse PG classification | NA |
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