| Gene Information | |
|---|---|
| Gene Name | NSMCE3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 304 |
| Protein Names | Non-structural maintenance of chromosomes element 3 homolog (Non-SMC element 3 homolog) (Hepatocellular carcinoma-associated protein 4) (MAGE-G1 antigen) (Melanoma-associated antigen G1) (Necdin-like protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 8 ( ENSG00000185115 ) 3 ( ENSG00000282130 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96MG7 |
| Gene Card | NSMCE3 |
| Uniprot ID | Q96MG7 |
| Pfam | PF01454 |
| In ASD | no |
| Allosteric Prediction | no (-1.482026041) |
| Ortholog in Animals | Mouse_ Nscme3l ( ortholog_one2many ) Mouse_ Nsmce3 ( ortholog_one2many ) Rat_ Nscme3l ( ortholog_one2one ) Rabbit_ NSMCE3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MAGED4, MAGED4B, MAGEB17, MAGEB1, MAGEA3, MAGEA6, MAGEL2, MAGEA2, MAGEA2B, MAGEA12, NDN, MAGEB6, MAGEB6B, MAGEB2, MAGEH1, MAGEA8, MAGEE2, MAGEA11, MAGEB5, MAGED1, MAGEB10, MAGEA10, MAGEA4, TRO, MAGEB4, MAGEC3, MAGEE1, MAGEA9, MAGEA9B, MAGEB3, MAGEC1, MAGEC2, MAGEA1, MAGEB18, MAGEB16, MAGEF1, MAGED2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:11782285}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.019773(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5HVQ (X-ray 2.92A ) 5WY5 (X-ray 2.92A ) |
| DBSNP | rs886037827 rs199905054 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:18086888}. Chromosome, telomere {ECO:0000305|PubMed:18086888}. |
| Mouse PG classification | NA |
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