| Gene Information | |
|---|---|
| Gene Name | NSMCE2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 247 |
| Protein Names | E3 SUMO-protein ligase NSE2 (EC 2.3.2.-) (E3 SUMO-protein transferase NSE2) (MMS21 homolog) (hMMS21) (Non-structural maintenance of chromosomes element 2 homolog) (Non-SMC element 2 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000156831 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96MF7 |
| Gene Card | NSMCE2 |
| Uniprot ID | Q96MF7 |
| Pfam | PF11789 |
| In ASD | no |
| Allosteric Prediction | no (-0.707621043) |
| Ortholog in Animals | Alpaca_ NSMCE2 ( ortholog_one2one ) Dog_ NSMCE2 ( ortholog_one2one ) GuineaPig_ NSMCE2 ( ortholog_one2one ) Macaque_ NSMCE2 ( ortholog_one2one ) Mouse_ Nsmce2 ( ortholog_one2one ) Pig_ NSMCE2 ( ortholog_one2one ) Rat_ Nsmce2 ( ortholog_one2one ) Rabbit_ NSMCE2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.051929(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2YU4 (NMR - ) |
| DBSNP | rs11542104 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:18086888}. Chromosome, telomere {ECO:0000269|PubMed:17589526}. Nucleus, PML body {ECO:0000269|PubMed:17589526}. Note=Localizes to PML nuclear bodies in ALT cell lines. {ECO:0000269|PubMed:17589526}. |
| Mouse PG classification | NA |
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