| Gene Information | |
|---|---|
| Gene Name | NSL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1105 |
| Protein Names | KAT8 regulatory NSL complex subunit 1 (MLL1/MLL complex subunit KANSL1) (MSL1 homolog 1) (hMSL1v1) (NSL complex protein NSL1) (Non-specific lethal 1 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000117697 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q7Z3B3 |
| Gene Card | KANSL1 |
| Uniprot ID | Q7Z3B3 |
| Pfam | PF15275 |
| In ASD | no |
| Allosteric Prediction | no (-0.878600278) |
| Ortholog in Animals | Alpaca_ NSL1 ( ortholog_one2one ) Dog_ NSL1 ( ortholog_one2one ) GuineaPig_ NSL1 ( ortholog_one2one ) Macaque_ NSL1 ( ortholog_one2one ) Mouse_ Nsl1 ( ortholog_one2one ) Pig_ NSL1 ( ortholog_one2one ) Rat_ Nsl1 ( ortholog_one2one ) Rabbit_ NSL1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the brain. {ECO:0000269|PubMed:11641718}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.062238(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4CY1 (X-ray 1.50A ) 4CY2 (X-ray 2.00A ) |
| DBSNP | rs17585974 rs17662853 rs35643216 rs34043286 rs7220988 rs34579536 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:20018852}. Nucleus. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:20813266}. |
| Mouse PG classification | NA |
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