Gene Information
Gene NameNSG2
OrganismHomo sapiens (Human)
Gene Length171
Protein NamesNeuronal vesicle trafficking-associated protein 2 (Neuron-specific protein family member 2) (Protein p19) (Hmp19)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000170091 )
Evolutionary StageVertebrata
AlphaFoldDBQ9Y328
Gene CardNSG2
Uniprot IDQ9Y328
PfamPF06387
In ASDno
Allosteric Predictionno (-0.99517475)
Ortholog in AnimalsAlpaca_ NSG2 ( ortholog_one2one )
Dog_ CPEB4 ( ortholog_one2one )
GuineaPig_ NSG2 ( ortholog_one2one )
Macaque_ NSG2 ( ortholog_one2one )
Mouse_ Nsg2 ( ortholog_one2one )
Pig_ NSG2 ( ortholog_one2one )
Rat_ Nsg2 ( ortholog_one2one )
Rabbit_ NSG2 ( ortholog_one2one )
OhnologsNA
ParalogsNSG1, CALY
Tissuebrain, cerebral.cortex
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane {ECO:0000250|UniProtKB:Q3KR51};
Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q3KR51}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q3KR51}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q3KR51}. Endosome membrane {ECO:0000250|UniProtKB:Q3KR51}. Early endosome membrane {ECO:0000250|UniProtKB:Q3KR51}. Late endosome membrane {ECO:0000250|UniProtKB:Q3KR51}. Lysosome lumen {ECO:0000250|UniProtKB:Q3KR51}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:P47759}. Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:P47759}. Endosome, multivesicular body membrane {ECO:0000250|UniProtKB:P47759}. Note=Endocytosed from the cell surface, thus entered into early endosomes, trafficks to late endosomes and degradates in lysosomes (By similarity). Mainly Golgi stack, but also found in small vacuolar organelles and multivesicular bodies. Found in both stationary and motile endosomes (By similarity). {ECO:0000250|UniProtKB:P47759, ECO:0000250|UniProtKB:Q3KR51}.
Mouse PG classificationNA
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