| Gene Information | |
|---|---|
| Gene Name | NSFL1C |
| Organism | Homo sapiens (Human) |
| Gene Length | 370 |
| Protein Names | NSFL1 cofactor p47 (UBX domain-containing protein 2C) (p97 cofactor p47) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000088833 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UNZ2 |
| Gene Card | NSFL1C |
| Uniprot ID | Q9UNZ2 |
| Pfam | PF08059; PF00789 |
| In ASD | no |
| Allosteric Prediction | no (-1.000319513) |
| Ortholog in Animals | Alpaca_ NSFL1C ( ortholog_one2one ) Dog_ NSFL1C ( ortholog_one2one ) GuineaPig_ NSFL1C ( ortholog_one2one ) Macaque_ NSFL1C ( ortholog_one2one ) Mouse_ Nsfl1c ( ortholog_one2one ) Pig_ NSFL1C ( ortholog_one2one ) Rat_ Nsfl1c ( ortholog_one2one ) Rabbit_ NSFL1C ( ortholog_one2one ) |
| Ohnologs | UBXN2A, UBXN2B |
| Paralogs | UBXN2B, UBXN2A, UBXN11 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.044503(Mouse);NULL(Rat);0.054545(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1SS6 (NMR - ) |
| DBSNP | rs9575 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:O35987}. Golgi apparatus, Golgi stack {ECO:0000250|UniProtKB:O35987}. Chromosome {ECO:0000250|UniProtKB:O35987}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:O35987}. Note=Predominantly nuclear in interphase cells. Bound to the axial elements of sex chromosomes in pachytene spermatocytes. A small proportion of the protein is cytoplasmic, associated with Golgi stacks. Localizes to centrosome during mitotic prophase and metaphase. {ECO:0000250|UniProtKB:O35987}. |
| Mouse PG classification | NA |
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