| Gene Information | |
|---|---|
| Gene Name | NRXN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 666 |
| Protein Names | Neurexin-2-beta (Neurexin II-beta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000110076 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P58401 |
| Gene Card | NRXN2 |
| Uniprot ID | P58401 |
| Pfam | PF02210 |
| In ASD | no |
| Allosteric Prediction | yes (0.162290063) |
| Ortholog in Animals | Alpaca_ NRXN2 ( ortholog_one2one ) Dog_ NRXN2 ( ortholog_one2one ) GuineaPig_ NRXN2 ( ortholog_one2one ) Macaque_ NRXN2 ( ortholog_one2one ) Mouse_ Nrxn2 ( ortholog_one2one ) Rat_ Nrxn2 ( ortholog_one2one ) Rabbit_ NRXN2 ( ortholog_one2one ) |
| Ohnologs | NRXN3, NRXN1 |
| Paralogs | CNTNAP3B, CNTNAP3, CNTNAP3C, CNTNAP4, PDGFD, ASTL, CNTNAP5, HEPH, MEP1A, CNTNAP2, MFRP, CUZD1, NETO2, TLL2, F5, PCOLCE, CP, NRP1, NRXN3, EDIL3, CNTNAP1, CUBN, MEP1B, NETO1, MFGE8, PCOLCE2, NRP2, HEPHL1, F8, TLL1, NRXN1, DCBLD2, PDGFC, CDCP2, BMP1 |
| Tissue | cerebral.cortex |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4NXR (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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