| Gene Information | |
|---|---|
| Gene Name | NRP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 931 |
| Protein Names | Neuropilin-2 (Vascular endothelial cell growth factor 165 receptor 2) |
| Target Name | neuropilin-2 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000118257 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O60462 |
| Gene Card | NRP2 |
| Uniprot ID | O60462 |
| Pfam | PF00431; PF11980; PF00754; PF00629 |
| In ASD | no |
| Allosteric Prediction | no (-0.411878794) |
| Ortholog in Animals | Alpaca_ NRP2 ( ortholog_one2one ) Dog_ NRP2 ( ortholog_one2one ) GuineaPig_ NRP2 ( ortholog_one2one ) Macaque_ NRP2 ( ortholog_one2one ) Mouse_ Nrp2 ( ortholog_one2one ) Pig_ NRP2 ( ortholog_one2one ) Rat_ Nrp2 ( ortholog_one2one ) Rabbit_ NRP2 ( ortholog_one2one ) |
| Ohnologs | NRP1 |
| Paralogs | CNTNAP3B, CNTNAP3, CNTNAP3C, CNTNAP4, PDGFD, ASTL, CNTNAP5, HEPH, MEP1A, NRXN2, CNTNAP2, MFRP, CUZD1, NETO2, TLL2, F5, PCOLCE, CP, NRP1, NRXN3, EDIL3, CNTNAP1, CUBN, MEP1B, NETO1, MFGE8, PCOLCE2, HEPHL1, F8, TLL1, NRXN1, DCBLD2, PDGFC, CDCP2, BMP1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2QQJ (X-ray 1.95A ) 2QQK (X-ray 2.75A ) 2QQL (X-ray 3.10A ) 2QQO (X-ray 2.30A ) 4QDQ (X-ray 1.95A ) 4QDR (X-ray 2.40A ) 4QDS (X-ray 2.40A ) 5DN2 (X-ray 1.95A ) 5DQ0 (X-ray 1.80A ) 6GH8 (X-ray 2.44A ) 6TDB (X-ray 2.45A ) 6TJT (X-ray 1.31A ) 7M22 (EM 3.65A ) 7T4S (EM 3.10A ) |
| DBSNP | rs849541 rs114144673 rs139711818 rs1128169 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:11112349}; Single-pass type I membrane protein {ECO:0000269|PubMed:11112349}.; [Isoform s9]: Secreted {ECO:0000269|PubMed:11112349}. |
| Mouse PG classification | NA |
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