| Gene Information | |
|---|---|
| Gene Name | CUZD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 607 |
| Protein Names | CUB and zona pellucida-like domain-containing protein 1 (CUB and ZP domain-containing protein 1) (Transmembrane protein UO-44) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000138161 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86UP6 |
| Gene Card | CUZD1 |
| Uniprot ID | Q86UP6 |
| Pfam | PF00431; PF00100 |
| In ASD | no |
| Allosteric Prediction | no (-0.881664168) |
| Ortholog in Animals | Alpaca_ CUZD1 ( ortholog_one2one ) Dog_ CUZD1 ( ortholog_one2one ) GuineaPig_ CUZD1 ( ortholog_one2one ) Macaque_ CUZD1 ( ortholog_one2one ) Mouse_ Cuzd1 ( ortholog_one2one ) Rat_ Cuzd1 ( ortholog_one2one ) Rabbit_ CUZD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MFRP, CNTNAP3B, CNTNAP3, CNTNAP3C, CNTNAP4, PDGFD, ASTL, CNTNAP5, HEPH, MEP1A, NRXN2, CNTNAP2, NETO2, TLL2, F5, PCOLCE, CP, NRP1, NRXN3, EDIL3, CNTNAP1, CUBN, MEP1B, NETO1, MFGE8, PCOLCE2, NRP2, HEPHL1, F8, TLL1, NRXN1, DCBLD2, PDGFC, CDCP2, BMP1 |
| Tissue | pancreas |
| Tissue Specificity | Detected in pancreas and epithelium of ovary. Expressed at higher levels in ovarian tumors than in normal tissue. {ECO:0000269|PubMed:15184879}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35120257 |
| Subcellular location [CC] | Zymogen granule membrane {ECO:0000250|UniProtKB:P70412}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P70412}. |
| Mouse PG classification | NA |
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