| Gene Information | |
|---|---|
| Gene Name | NRP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 816 |
| Protein Names | Protein kinase C-binding protein NELL2 (NEL-like protein 2) (Nel-related protein 2) |
| Target Name | neuropilin-2 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000118257 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q99435 |
| Gene Card | NELL2 |
| Uniprot ID | Q99435 |
| Pfam | PF12947; PF07645; PF02210; PF00093 |
| In ASD | no |
| Allosteric Prediction | no (-0.411878794) |
| Ortholog in Animals | Alpaca_ NRP2 ( ortholog_one2one ) Dog_ NRP2 ( ortholog_one2one ) GuineaPig_ NRP2 ( ortholog_one2one ) Macaque_ NRP2 ( ortholog_one2one ) Mouse_ Nrp2 ( ortholog_one2one ) Pig_ NRP2 ( ortholog_one2one ) Rat_ Nrp2 ( ortholog_one2one ) Rabbit_ NRP2 ( ortholog_one2one ) |
| Ohnologs | NRP1 |
| Paralogs | CNTNAP3B, CNTNAP3, CNTNAP3C, CNTNAP4, PDGFD, ASTL, CNTNAP5, HEPH, MEP1A, NRXN2, CNTNAP2, MFRP, CUZD1, NETO2, TLL2, F5, PCOLCE, CP, NRP1, NRXN3, EDIL3, CNTNAP1, CUBN, MEP1B, NETO1, MFGE8, PCOLCE2, HEPHL1, F8, TLL1, NRXN1, DCBLD2, PDGFC, CDCP2, BMP1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6POG (X-ray 2.75A ) |
| DBSNP | rs2658973 rs17574839 rs1050710 |
| Subcellular location [CC] | Secreted {ECO:0000250|UniProtKB:Q62918}. |
| Mouse PG classification | NA |
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