| Gene Information | |
|---|---|
| Gene Name | NRL |
| Organism | Homo sapiens (Human) |
| Gene Length | 237 |
| Protein Names | Neural retina-specific leucine zipper protein (NRL) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000129535 ) 3 ( ENSG00000285493 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P54845 |
| Gene Card | NRL |
| Uniprot ID | P54845 |
| Pfam | PF03131; PF08383 |
| In ASD | no |
| Allosteric Prediction | no (-1.235544526) |
| Ortholog in Animals | Alpaca_ NRL ( ortholog_one2one ) Dog_ NRL ( ortholog_one2one ) GuineaPig_ NRL ( ortholog_one2one ) Macaque_ NRL ( ortholog_one2one ) Mouse_ Nrl ( ortholog_one2one ) Pig_ NRL ( ortholog_one2one ) Rat_ Nrl ( ortholog_one2one ) Rabbit_ NRL ( ortholog_one2one ) |
| Ohnologs | MAF, MAFB, MAFA |
| Paralogs | MAFF, MAFA, MAF, MAFG, MAFK, MAFB |
| Tissue | NA |
| Tissue Specificity | Expressed in the brain and the retina (PubMed:11477108). Expressed strongly in rod and cone cells (at protein level) (PubMed:11477108). {ECO:0000269|PubMed:11477108}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs104894459 rs794727281 rs199691910 rs149921817 rs397514516 rs757038765 rs201970559 rs104894463 rs1173385399 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11477108}. Nucleus {ECO:0000269|PubMed:11477108, ECO:0000269|PubMed:17335001}. |
| Mouse PG classification | HPG |
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