| Gene Information | |
|---|---|
| Gene Name | NRIF3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 177 |
| Protein Names | Centromere protein R (CENP-R) (Beta-3-endonexin) (Integrin beta-3-binding protein) (Nuclear receptor-interacting factor 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q13352 |
| Gene Card | ITGB3BP |
| Uniprot ID | Q13352 |
| Pfam | PF06729 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in spleen, thymus, prostate, ovary, small intestine and white blood cells. Highly expressed in testis and colon. Isoform 4 is expressed in platelets, lymphocytes and granulocytes. {ECO:0000269|PubMed:11864709, ECO:0000269|PubMed:7593198}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7PB8 (X-ray 3.68A ) 7PKN (EM 3.20A ) 7QOO (EM 4.60A ) 7R5S (EM 2.83A ) 7R5V (EM 4.55A ) 7YWX (EM 12.00A ) 7YYH (EM 8.90A ) |
| DBSNP | rs1058057 |
| Subcellular location [CC] | [Isoform 1]: Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore.; [Isoform 2]: Nucleus.; [Isoform 3]: Nucleus. Cytoplasm. Note=Isoform 3 is predominantly nuclear and weakly cytoplasmic.; [Isoform 4]: Cytoplasm. |
| Mouse PG classification | NA |
| click here to return to the previous page | |