| Gene Information | |
|---|---|
| Gene Name | TUSC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 212 |
| Protein Names | Tumor suppressor candidate gene 1 protein (TSG-9) (TSG9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000198680 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q2TAM9 |
| Gene Card | TUSC1 |
| Uniprot ID | Q2TAM9 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.777382324) |
| Ortholog in Animals | Alpaca_ TUSC1 ( ortholog_one2one ) Dog_ TUSC1 ( ortholog_one2one ) Macaque_ TUSC1 ( ortholog_one2one ) Mouse_ Tusc1 ( ortholog_one2one ) Pig_ TUSC1 ( ortholog_one2one ) Rat_ Tusc1 ( ortholog_one2one ) Rabbit_ TUSC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed at low level. Expressed at higher level in testis, weakly expressed in muscle, colon, lung and spleen. Not detected in 3 non small cell lung carcinoma (NSCLC) cell lines with homozygous deletion of the 9p region, while it is down-regulated in 3 other tumor cell lines. {ECO:0000269|PubMed:15208665}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34498078 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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