| Gene Information | |
|---|---|
| Gene Name | NRDE2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1164 |
| Protein Names | Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000119720 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H7Z3 |
| Gene Card | NRDE2 |
| Uniprot ID | Q9H7Z3 |
| Pfam | PF08424 |
| In ASD | no |
| Allosteric Prediction | no (-1.030920793) |
| Ortholog in Animals | Alpaca_ NRDE2 ( ortholog_one2one ) Dog_ NRDE2 ( ortholog_one2one ) GuineaPig_ NRDE2 ( ortholog_one2one ) Mouse_ Nrde2 ( ortholog_one2one ) Pig_ NRDE2 ( ortholog_one2one ) Rat_ Nrde2 ( ortholog_one2one ) Rabbit_ NRDE2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.075380(Chimpanzee);0.033983(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6IEH (X-ray 2.89A ) |
| DBSNP | rs7140914 rs59039343 rs3737035 |
| Subcellular location [CC] | Nucleus speckle {ECO:0000269|PubMed:30538148, ECO:0000269|PubMed:30842217}. Nucleus, nucleolus {ECO:0000269|PubMed:30842217}. Nucleus, nucleoplasm {ECO:0000269|PubMed:30538148, ECO:0000269|PubMed:30842217}. Nucleus {ECO:0000269|PubMed:29902117}. |
| Mouse PG classification | NA |
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