| Gene Information | |
|---|---|
| Gene Name | NRDC |
| Organism | Homo sapiens (Human) |
| Gene Length | 1151 |
| Protein Names | Nardilysin (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C) (Nardilysin convertase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000078618 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O43847 |
| Gene Card | NRDC |
| Uniprot ID | O43847 |
| Pfam | PF00675; PF05193; PF16187 |
| In ASD | no |
| Allosteric Prediction | no (-0.286304426) |
| Ortholog in Animals | Alpaca_ NRDC ( ortholog_one2one ) Dog_ NRDC ( ortholog_one2one ) GuineaPig_ NRDC ( ortholog_one2one ) Macaque_ NRDC ( ortholog_one2one ) Mouse_ Nrd1 ( ortholog_one2one ) Pig_ NRDC ( ortholog_one2one ) Rat_ Nrdc ( ortholog_one2one ) Rabbit_ NRDC ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PMPCA, UQCRC1, PITRM1, UQCRC2, PMPCB, IDE |
| Tissue | NA |
| Tissue Specificity | Primarily in adult heart, skeletal muscle, and testis and at much lower levels in other tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34957144 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:28017472}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q8BHG1}. |
| Mouse PG classification | NA |
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