| Gene Information | |
|---|---|
| Gene Name | KIAA1991 |
| Organism | Homo sapiens (Human) |
| Gene Length | 708 |
| Protein Names | E3 ubiquitin-protein ligase RNF169 (EC 2.3.2.27) (RING finger protein 169) (RING-type E3 ubiquitin transferase RNF169) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8NCN4 |
| Gene Card | RNF169 |
| Uniprot ID | Q8NCN4 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5GG4 (X-ray 3.11A ) 5VEY (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Chromosome {ECO:0000269|PubMed:30104380, ECO:0000269|PubMed:30773093}. Nucleus, nucleoplasm {ECO:0000269|PubMed:22492721, ECO:0000269|PubMed:22733822, ECO:0000269|PubMed:22742833}. Note=Localizes to sites of double-strand breaks (DSBs) following DNA damage. Recruited to DSBs via recognition of RNF168-dependent ubiquitin products. {ECO:0000269|PubMed:30104380}. |
| Mouse PG classification | NA |
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