| Gene Information | |
|---|---|
| Gene Name | NUP107 |
| Organism | Homo sapiens (Human) |
| Gene Length | 925 |
| Protein Names | Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000111581 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P57740 |
| Gene Card | NUP107 |
| Uniprot ID | P57740 |
| Pfam | PF04121 |
| In ASD | no |
| Allosteric Prediction | no (-0.086013221) |
| Ortholog in Animals | Alpaca_ NUP107 ( ortholog_one2one ) Dog_ NUP107 ( ortholog_one2one ) GuineaPig_ NUP107 ( ortholog_one2one ) Macaque_ NUP107 ( ortholog_one2one ) Mouse_ Nup107 ( ortholog_one2one ) Pig_ NUP107 ( ortholog_one2one ) Rat_ Nup107 ( ortholog_one2one ) Rabbit_ NUP107 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed in fetal and adult tissues. {ECO:0000269|PubMed:26411495}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002280(Rat);0.059259(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 3CQC (X-ray 2.53A ) 3CQG (X-ray 3.00A ) 3I4R (X-ray 3.53A ) 5A9Q (EM 23.00A ) 7PEQ (EM 35.00A ) 7R5K (EM 12.00A ) |
| DBSNP | rs730882216 rs864321633 rs745342141 rs1555178358 rs864321632 rs1565707103 |
| Subcellular location [CC] | Nucleus membrane {ECO:0000269|PubMed:11564755, ECO:0000269|PubMed:12802065, ECO:0000269|PubMed:15229283, ECO:0000269|PubMed:26411495}. Nucleus, nuclear pore complex {ECO:0000269|PubMed:11564755, ECO:0000269|PubMed:12802065, ECO:0000269|PubMed:15229283, ECO:0000269|PubMed:26411495}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:11564755}. Note=Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). Dissociates from the dissasembled NPC structure late during prophase of mitosis (PubMed:11564755). {ECO:0000269|PubMed:11564755}. |
| Mouse PG classification | NA |
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