Gene Information
Gene NameNR1C2
OrganismHomo sapiens (Human)
Gene Length441
Protein NamesPeroxisome proliferator-activated receptor delta (PPAR-delta) (NUCI) (Nuclear hormone receptor 1) (NUC1) (Nuclear receptor subfamily 1 group C member 2) (Peroxisome proliferator-activated receptor beta) (PPAR-beta)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ03181
Gene CardPPARD
Uniprot IDQ03181
PfamPF00104; PF00105
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitous with maximal levels in placenta and skeletal muscle.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1GWX  (X-ray  2.50A  1Y0S  (X-ray  2.65A  2AWH  (X-ray  2.00A  2B50  (X-ray  2.00A  2BAW  (X-ray  2.30A  2ENV  (NMR  2GWX  (X-ray  2.30A  2J14  (X-ray  2.80A  2Q5G  (X-ray  2.70A  2XYJ  (X-ray  2.30A  2XYW  (X-ray  3.14A  2XYX  (X-ray  2.70A  2ZNP  (X-ray  3.00A  2ZNQ  (X-ray  2.65A  3D5F  (X-ray  2.20A  3DY6  (X-ray  2.90A  3ET2  (X-ray  2.24A  3GWX  (X-ray  2.40A  3GZ9  (X-ray  2.00A  3OZ0  (X-ray  3.00A  3PEQ  (X-ray  2.40A  3SP9  (X-ray  2.30A  3TKM  (X-ray  1.95A  5U3Q  (X-ray  1.50A  5U3R  (X-ray  1.95A  5U3S  (X-ray  2.00A  5U3T  (X-ray  1.70A  5U3U  (X-ray  2.10A  5U3V  (X-ray  1.84A  5U3W  (X-ray  1.80A  5U3X  (X-ray  2.10A  5U3Y  (X-ray  1.90A  5U3Z  (X-ray  1.72A  5U40  (X-ray  2.00A  5U41  (X-ray  1.90A  5U42  (X-ray  1.70A  5U43  (X-ray  1.90A  5U44  (X-ray  2.15A  5U45  (X-ray  1.95A  5U46  (X-ray  2.00A  5XMX  (X-ray  2.00A  5Y7X  (X-ray  1.70A  5ZXI  (X-ray  2.10A  6A6P  (X-ray  2.10A  7F80  (X-ray  2.80A  7VWE  (X-ray  3.00A  7VWF  (X-ray  1.90A  7VWG  (X-ray  2.20A  7VWH  (X-ray  2.10A  7W0G  (X-ray  2.44A  7WGL  (X-ray  2.09A  7WGN  (X-ray  1.81A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:35675826}.
Mouse PG classificationNA
click here to return to the previous page