| Gene Information | |
|---|---|
| Gene Name | NQO2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 231 |
| Protein Names | Ribosyldihydronicotinamide dehydrogenase [quinone] (EC 1.10.5.1) (NRH dehydrogenase [quinone] 2) (NRH:quinone oxidoreductase 2) (Quinone reductase 2) (QR2) |
| Target Name | ribosyldihydronicotinamide dehydrogenase [quinone] |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000124588 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P16083 |
| Gene Card | NQO2 |
| Uniprot ID | P16083 |
| Pfam | PF02525 |
| In ASD | no |
| Allosteric Prediction | yes (0.375675487) |
| Ortholog in Animals | Alpaca_ NQO2 ( ortholog_one2one ) Dog_ NQO2 ( ortholog_one2one ) GuineaPig_ NQO2 ( ortholog_one2one ) Macaque_ NQO2 ( ortholog_one2one ) Mouse_ Nqo2 ( ortholog_one2one ) Pig_ NQO2 ( ortholog_one2one ) Rat_ Nqo2 ( ortholog_one2many ) Rat_ AABR07044714.1 ( ortholog_one2many ) Rabbit_ NQO2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NQO1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1QR2 (X-ray 2.10A ) 1SG0 (X-ray 1.50A ) 1XI2 (X-ray 1.50A ) 1ZX1 (X-ray 2.16A ) 2BZS (X-ray 2.00A ) 2QMY (X-ray 2.50A ) 2QMZ (X-ray 2.10A ) 2QR2 (X-ray 2.45A ) 2QWX (X-ray 1.50A ) 2QX4 (X-ray 1.65A ) 2QX6 (X-ray 1.75A ) 2QX8 (X-ray 1.60A ) 2QX9 (X-ray 2.31A ) 3FW1 (X-ray 1.75A ) 3G5M (X-ray 1.84A ) 3GAM (X-ray 1.98A ) 3NFR (X-ray 1.57A ) 3NHF (X-ray 2.00A ) 3NHJ (X-ray 2.33A ) 3NHK (X-ray 1.96A ) 3NHL (X-ray 1.57A ) 3NHP (X-ray 1.70A ) 3NHR (X-ray 1.80A ) 3NHS (X-ray 1.78A ) 3NHU (X-ray 1.90A ) 3NHW (X-ray 1.65A ) 3NHY (X-ray 1.90A ) 3O2N (X-ray 1.60A ) 3O73 (X-ray 2.00A ) 3OVM (X-ray 2.09A ) 3OWH (X-ray 2.28A ) 3OWX (X-ray 1.85A ) 3OX1 (X-ray 2.00A ) 3OX2 (X-ray 2.41A ) 3OX3 (X-ray 1.80A ) 3TE7 (X-ray 1.70A ) 3TEM (X-ray 1.45A ) 3TZB (X-ray 2.19A ) 3UXE (X-ray 1.50A ) 3UXH (X-ray 1.53A ) 4FGJ (X-ray 1.35A ) 4FGK (X-ray 1.40A ) 4FGL (X-ray 1.20A ) 4GQI (X-ray 1.95A ) 4GR9 (X-ray 2.29A ) 4QOD (X-ray 1.35A ) 4QOE (X-ray 1.45A ) 4QOF (X-ray 1.55A ) 4QOG (X-ray 1.40A ) 4QOH (X-ray 1.60A ) 4QOI (X-ray 1.55A ) 4QOJ (X-ray 1.85A ) 4U7F (X-ray 1.80A ) 4U7G (X-ray 1.96A ) 4U7H (X-ray 1.48A ) 4XDG (X-ray 1.50A ) 4XDH (X-ray 1.90A ) 4ZVK (X-ray 1.87A ) 4ZVL (X-ray 1.90A ) 4ZVM (X-ray 1.97A ) 4ZVN (X-ray 1.87A ) 5BUC (X-ray 1.87A ) 5LBT (X-ray 1.75A ) 5LBU (X-ray 1.65A ) 5LBW (X-ray 1.90A ) 5LBY (X-ray 1.40A ) 5LBZ (X-ray 1.40A ) 7O4D (X-ray 2.25A ) |
| DBSNP | rs28383623 rs17136117 rs1143684 rs17300141 rs28383651 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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