| Gene Information | |
|---|---|
| Gene Name | NPY |
| Organism | Homo sapiens (Human) |
| Gene Length | 97 |
| Protein Names | Pro-neuropeptide Y [Cleaved into: Neuropeptide Y (Neuropeptide tyrosine) (NPY); C-flanking peptide of NPY (CPON)] |
| Target Name | pro-neuropeptide y |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000122585 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P01303 |
| Gene Card | NPY |
| Uniprot ID | P01303 |
| Pfam | PF00159 |
| In ASD | no |
| Allosteric Prediction | no (-0.165461805) |
| Ortholog in Animals | Alpaca_ NPY ( ortholog_one2one ) Dog_ NPY ( ortholog_one2one ) GuineaPig_ NPY ( ortholog_one2one ) Macaque_ NPY ( ortholog_one2one ) Mouse_ Npy ( ortholog_one2one ) Pig_ NPY ( ortholog_one2one ) Rat_ Npy ( ortholog_one2one ) Rabbit_ NPY ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PPY, PYY |
| Tissue | prostate, caudate.nucleus, nucleus.accumbens, putamen |
| Tissue Specificity | One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1QFA (NMR - ) 1RON (NMR - ) 7RTA (X-ray 2.60A ) 7VGX (EM 3.20A ) 7X9A (EM 3.20A ) 7X9B (EM 3.40A ) |
| DBSNP | rs16139 rs5571 |
| Subcellular location [CC] | Secreted. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle {ECO:0000250|UniProtKB:P07808}. |
| Mouse PG classification | NA |
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