| Gene Information | |
|---|---|
| Gene Name | NPW |
| Organism | Homo sapiens (Human) |
| Gene Length | 165 |
| Protein Names | Neuropeptide W (Preproprotein L8) (hPPL8) [Cleaved into: Neuropeptide W-23 (NPW23) (hL8); Neuropeptide W-30 (NPW30) (hL8C)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000183971 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q8N729 |
| Gene Card | NPW |
| Uniprot ID | Q8N729 |
| Pfam | PF15180 |
| In ASD | no |
| Allosteric Prediction | no (-0.139211268) |
| Ortholog in Animals | Alpaca_ NPW ( ortholog_one2one ) Macaque_ NPW ( ortholog_one2one ) Mouse_ Npw ( ortholog_one2one ) Pig_ NPW ( ortholog_one2one ) Rat_ Npw ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NPB |
| Tissue | pituitary.gland, placenta |
| Tissue Specificity | Detected at high levels in the substantia nigra, fetal kidney and trachea; at lower levels in testis, uterus, ovary and placenta. Not detectable in many regions of the central nervous system. Also detected at high levels in lymphoblastic leukemia and colorectal adenocarcinoma. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2286472 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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