Gene Information
Gene NameNPT4
OrganismHomo sapiens (Human)
Gene Length420
Protein NamesSodium-dependent phosphate transport protein 4 (Na(+)/PI cotransporter 4) (NPT4) (Sodium/phosphate cotransporter 4) (Solute carrier family 17 member 3)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBO00476
Gene CardSLC17A3
Uniprot IDO00476
PfamPF07690
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in the liver and kidney (PubMed:9149941, PubMed:20810651). It is detected in proximal tubules in renal cortex as well as some tubules and glomeruli, with highest expression at the apical side of proximal tubules (at protein level) (PubMed:20810651). {ECO:0000269|PubMed:20810651, ECO:0000269|PubMed:9149941}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs387907257  rs1165165  rs56027330  rs387907256  rs11966370 
Subcellular location [CC][Isoform 1]: Endoplasmic reticulum membrane {ECO:0000269|PubMed:15505377};
Multi-pass membrane protein {ECO:0000269|PubMed:15505377}.;
[Isoform 2]: Cell membrane {ECO:0000269|PubMed:20810651};
Multi-pass membrane protein {ECO:0000269|PubMed:20810651}.
Mouse PG classificationNA
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