Gene Information
Gene NameNPLOC4
OrganismHomo sapiens (Human)
Gene Length608
Protein NamesNuclear protein localization protein 4 homolog (Protein NPL4)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000182446 )
Evolutionary StageEukaryota
AlphaFoldDBQ8TAT6
Gene CardNPLOC4
Uniprot IDQ8TAT6
PfamPF05021; PF11543; PF05020
In ASDno
Allosteric Predictionno (-0.816749806)
Ortholog in AnimalsAlpaca_ NPLOC4 ( ortholog_one2one )
Dog_ NPLOC4 ( ortholog_one2one )
GuineaPig_ NPLOC4 ( ortholog_one2one )
Macaque_ NPLOC4 ( ortholog_one2one )
Mouse_ Nploc4 ( ortholog_one2one )
Pig_ NPLOC4 ( ortholog_one2one )
Rat_ Nploc4 ( ortholog_one2one )
Rabbit_ NPLOC4 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed at highest levels in brain, heart, skeletal muscle, kidney and fetal liver. {ECO:0000269|PubMed:11574150}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9ES54}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9ES54}. Nucleus {ECO:0000250|UniProtKB:Q9ES54}. Note=Associated with the endoplasmic reticulum and nuclear. {ECO:0000250|UniProtKB:Q9ES54}.
Mouse PG classificationNA
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