| Gene Information | |
|---|---|
| Gene Name | TAS2R14 |
| Organism | Homo sapiens (Human) |
| Gene Length | 317 |
| Protein Names | Taste receptor type 2 member 14 (T2R14) (Taste receptor family B member 1) (TRB1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 36 ( ENSG00000212127 ) 3 ( ENSG00000261984 ) 3 ( ENSG00000276541 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9NYV8 |
| Gene Card | TAS2R14 |
| Uniprot ID | Q9NYV8 |
| Pfam | PF05296 |
| In ASD | yes |
| Allosteric Prediction | yes (0.999955672) |
| Ortholog in Animals | Alpaca_ TAS2R14 ( ortholog_one2one ) Macaque_ TAS2R14 ( ortholog_one2one ) Mouse_ Tas2r116 ( ortholog_one2many ) Mouse_ Tas2r129 ( ortholog_one2many ) Mouse_ Tas2r110 ( ortholog_one2many ) Mouse_ Tas2r140 ( ortholog_one2many ) Mouse_ Tas2r109 ( ortholog_one2many ) Mouse_ Tas2r113 ( ortholog_one2many ) Mouse_ Tas2r117 ( ortholog_one2many ) Mouse_ Tas2r125 ( ortholog_one2many ) Mouse_ Tas2r103 ( ortholog_one2many ) Mouse_ Tas2r123 ( ortholog_one2many ) Mouse_ Tas2r115 ( ortholog_one2many ) Rat_ Tas2r116 ( ortholog_one2many ) Rat_ Tas2r129 ( ortholog_one2many ) Rat_ Tas2r110 ( ortholog_one2many ) Rat_ Tas2r109 ( ortholog_one2many ) Rat_ Tas2r140 ( ortholog_one2many ) Rat_ Tas2r113 ( ortholog_one2many ) Rat_ Tas2r125 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | TAS2R20, TAS2R50, TAS2R43, TAS2R19, TAS2R30, TAS2R46, TAS2R31, TAS2R13, TAS2R42, TAS2R10, TAS2R9, TAS2R8, TAS2R7, TAS2R3, TAS2R5, TAS2R38, TAS2R1, TAS2R41, TAS2R60, TAS2R16, TAS2R4, TAS2R39, TAS2R40 |
| Tissue | substantia.nigra |
| Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Expressed in testis (PubMed:16720576). {ECO:0000269|PubMed:16720576}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs16925868 rs35804287 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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