| Gene Information | |
|---|---|
| Gene Name | NPAS3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 933 |
| Protein Names | Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Basic-helix-loop-helix-PAS protein MOP6) (Class E basic helix-loop-helix protein 12) (bHLHe12) (Member of PAS protein 6) (PAS domain-containing protein 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000151322 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8IXF0 |
| Gene Card | NPAS3 |
| Uniprot ID | Q8IXF0 |
| Pfam | PF00989; PF08447 |
| In ASD | no |
| Allosteric Prediction | no (-0.796484119) |
| Ortholog in Animals | Alpaca_ NPAS3 ( ortholog_one2one ) Dog_ NPAS3 ( ortholog_one2one ) GuineaPig_ NPAS3 ( ortholog_one2one ) Macaque_ NPAS3 ( ortholog_one2one ) Mouse_ Npas3 ( ortholog_one2one ) Pig_ NPAS3 ( ortholog_one2one ) Rat_ Npas3 ( ortholog_one2one ) Rabbit_ NPAS3 ( ortholog_one2one ) |
| Ohnologs | NPAS1, SIM1 |
| Paralogs | EPAS1, SIM1, NPAS1, SIM2, NPAS4, HIF1A, HIF3A |
| Tissue | brain |
| Tissue Specificity | Ubiquitously expressed in the adult brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:12746393}. |
| Mouse PG classification | NA |
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