Gene Information
Gene NameMC5R
OrganismHomo sapiens (Human)
Gene Length325
Protein NamesMelanocortin receptor 5 (MC5-R) (MC-2)
Target Namemelanocortin receptor 5
Target TypeNA
Gene Age12 ( ENSG00000176136 )
Evolutionary StageEumetazoa
AlphaFoldDBP33032
Gene CardMC5R
Uniprot IDP33032
PfamPF00001
In ASDyes
Allosteric Predictionyes (0.999982005)
Ortholog in AnimalsDog_ MC5R ( ortholog_one2one )
GuineaPig_ MC5R ( ortholog_one2one )
Mouse_ Mc5r ( ortholog_one2one )
Pig_ MC5R ( ortholog_one2one )
Rat_ Mc5r ( ortholog_one2one )
Rabbit_ MC5R ( ortholog_one2one )
OhnologsMC3R, MC4R
ParalogsS1PR1, S1PR5, S1PR2, S1PR3, S1PR4, LPAR1, LPAR2, LPAR3, GPR3, GPR119, GPR6, GPR12, CNR1, CNR2, MC2R, MC3R, MC4R, MC1R
TissueNA
Tissue SpecificityExpressed in the brain but not in the melanoma cells.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2236700 
Subcellular location [CC]Cell membrane;
Multi-pass membrane protein.
Mouse PG classificationNA
click here to return to the previous page