| Gene Information | |
|---|---|
| Gene Name | NOT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 540 |
| Protein Names | CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NZN8 |
| Gene Card | CNOT2 |
| Uniprot ID | Q9NZN8 |
| Pfam | PF04153 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:10637334}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.068174(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4C0D (X-ray 3.20A ) 4C0F (X-ray 2.40A ) 5FU6 (X-ray 2.90A ) 5FU7 (X-ray 3.10A ) |
| DBSNP | rs11178192 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:21299754}. Nucleus {ECO:0000305|PubMed:21299754}. |
| Mouse PG classification | NA |
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