| Gene Information | |
|---|---|
| Gene Name | CRYL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 319 |
| Protein Names | Lambda-crystallin homolog (EC 1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000165475 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9Y2S2 |
| Gene Card | CRYL1 |
| Uniprot ID | Q9Y2S2 |
| Pfam | PF00725; PF02737 |
| In ASD | no |
| Allosteric Prediction | no (-0.702335091) |
| Ortholog in Animals | Alpaca_ CRYL1 ( ortholog_one2one ) Dog_ CRYL1 ( ortholog_one2one ) GuineaPig_ CRYL1 ( ortholog_one2one ) Macaque_ CRYL1 ( ortholog_one2one ) Mouse_ Cryl1 ( ortholog_one2one ) Pig_ CRYL1 ( ortholog_one2one ) Rat_ Cryl1 ( ortholog_one2one ) Rabbit_ CRYL1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HADH, EHHADH, HADHA |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest levels in liver and kidney. {ECO:0000269|PubMed:12527201}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3F3S (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:P14755}. |
| Mouse PG classification | NA |
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