Gene Information
Gene NameNOP58
OrganismHomo sapiens (Human)
Gene Length529
Protein NamesNucleolar protein 58 (Nucleolar protein 5)
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000055044 )
Evolutionary StageEuk_Archaea
AlphaFoldDBQ9Y2X3
Gene CardNOP58
Uniprot IDQ9Y2X3
PfamPF01798; PF08156
In ASDno
Allosteric Predictionno (-0.816704258)
Ortholog in AnimalsAlpaca_ NOP58 ( ortholog_one2one )
Dog_ NOP58 ( ortholog_one2one )
GuineaPig_ NOP58 ( ortholog_one2one )
Macaque_ NOP58 ( ortholog_one2one )
Mouse_ Nop58 ( ortholog_one2one )
Pig_ NOP58 ( ortholog_one2one )
Rat_ Nop58 ( ortholog_one2one )
Rabbit_ NOP58 ( ortholog_one2one )
OhnologsNA
ParalogsNOP56
TissueNA
Tissue SpecificityUbiquitous.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.453460(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7MQ8  (EM  3.60A  7MQ9  (EM  3.87A  7MQA  (EM  2.70A 
DBSNP rs34748654  rs34458926  rs35900977  rs34523815 
Subcellular location [CC]Nucleus, nucleolus {ECO:0000269|PubMed:33367824}. Nucleus, nucleoplasm {ECO:0000269|PubMed:33367824}. Note=Localizes to the nucleolus with a minor part present in the nucleoplasm. {ECO:0000269|PubMed:33367824}.
Mouse PG classificationNA
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