| Gene Information | |
|---|---|
| Gene Name | NOL8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1167 |
| Protein Names | Nucleolar protein 8 (Nucleolar protein Nop132) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000198000 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q76FK4 |
| Gene Card | NOL8 |
| Uniprot ID | Q76FK4 |
| Pfam | PF00076 |
| In ASD | no |
| Allosteric Prediction | no (-1.103267003) |
| Ortholog in Animals | Alpaca_ NOL8 ( ortholog_one2one ) Dog_ NOL8 ( ortholog_one2one ) Macaque_ NOL8 ( ortholog_one2one ) Mouse_ Nol8 ( ortholog_one2one ) Pig_ NOL8 ( ortholog_one2one ) Rat_ Nol8 ( ortholog_one2one ) Rabbit_ NOL8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle. {ECO:0000269|PubMed:15132771}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.070650(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs58545014 rs2236344 rs15717 rs34224798 rs921122 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:15132771, ECO:0000269|PubMed:16963496}. Note=Localizes in the nucleolar-organizing region during ribosome biogenesis. |
| Mouse PG classification | NA |
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