| Gene Information | |
|---|---|
| Gene Name | NOE2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 454 |
| Protein Names | Noelin-2 (Olfactomedin-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O95897 |
| Gene Card | OLFM2 |
| Uniprot ID | O95897 |
| Pfam | PF12308; PF02191 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in aortic smooth muscle (at protein level) (PubMed:25298399). In the fetus, expressed in the brain and ocular tissues including lens vesicle and optic cup (PubMed:27844144). {ECO:0000269|PubMed:25298399, ECO:0000269|PubMed:27844144}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1298178636 rs2303100 rs11556087 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:21228389}. Synapse {ECO:0000250|UniProtKB:Q8BM13}. Membrane {ECO:0000250|UniProtKB:Q8BM13}. Nucleus {ECO:0000269|PubMed:25298399}. Cytoplasm {ECO:0000269|PubMed:25298399}. Note=Nuclear localization is induced by TGF-beta. {ECO:0000269|PubMed:25298399}. |
| Mouse PG classification | NA |
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