| Gene Information | |
|---|---|
| Gene Name | NOD6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 991 |
| Protein Names | NACHT, LRR and PYD domains-containing protein 9 (Nucleotide-binding oligomerization domain protein 6) (PYRIN and NACHT-containing protein 12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q7RTR0 |
| Gene Card | NLRP9 |
| Uniprot ID | Q7RTR0 |
| Pfam | PF13516; PF05729; PF17776; PF17779; PF02758 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in ileum intestinal epithelial cells. Not detected in peripheral blood mononuclear cells (PubMed:28636595). Expressed in cerebral endothelial cells and, at much lower levels, in brain pericytes (PubMed:28432035). {ECO:0000269|PubMed:28432035, ECO:0000269|PubMed:28636595}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6Z2G (X-ray 1.95A ) 7BSO (X-ray 2.08A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q66X22}. Inflammasome {ECO:0000269|PubMed:28636595}. |
| Mouse PG classification | NA |
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