Gene Information
Gene NameNOCT
OrganismHomo sapiens (Human)
Gene Length431
Protein NamesNocturnin (EC 3.1.3.108) (Carbon catabolite repression 4-like protein)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000151014 )
Evolutionary StageEukaryota
AlphaFoldDBQ9UK39
Gene CardNOCT
Uniprot IDQ9UK39
PfamPF03372
In ASDno
Allosteric Predictionno (-0.204362457)
Ortholog in AnimalsAlpaca_ NOCT ( ortholog_one2one )
Dog_ NOCT ( ortholog_one2one )
GuineaPig_ NOCT ( ortholog_one2one )
Macaque_ NOCT ( ortholog_one2one )
Mouse_ Noct ( ortholog_one2one )
Pig_ NOCT ( ortholog_one2one )
Rat_ Noct ( ortholog_one2one )
Rabbit_ NOCT ( ortholog_one2one )
OhnologsNA
ParalogsCNOT6, ANGEL2, PDE12, CNOT6L, ANGEL1
TissueNA
Tissue SpecificityAdipose tissue. Expression is higher in subcutaneous adipose tissue as compared to visceral adipose tissue. {ECO:0000269|PubMed:22331129}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.075(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6BT1  (X-ray  1.48A  6BT2  (X-ray  2.41A  6MAL  (X-ray  2.60A  6NF0  (X-ray  2.70A 
DBSNP rs2271777 
Subcellular location [CC]Cytoplasm {ECO:0000250|UniProtKB:O35710}. Nucleus {ECO:0000250|UniProtKB:O35710}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O35710}. Mitochondrion {ECO:0000269|PubMed:31147539}.
Mouse PG classificationNA
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