| Gene Information | |
|---|---|
| Gene Name | NO66 |
| Organism | Homo sapiens (Human) |
| Gene Length | 641 |
| Protein Names | Ribosomal oxygenase 1 (60S ribosomal protein L8 histidine hydroxylase) (Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66) (EC 1.14.11.-, EC 1.14.11.27) (Myc-associated protein with JmjC domain) (Nucleolar protein 66) (hsNO66) (Ribosomal oxygenase NO66) (ROX) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9H6W3 |
| Gene Card | RIOX1 |
| Uniprot ID | Q9H6W3 |
| Pfam | PF08007 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Overexpressed in lung carcinomas. {ECO:0000269|PubMed:14742713, ECO:0000269|PubMed:17308053}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4CCJ (X-ray 2.15A ) 4CCK (X-ray 2.15A ) 4CCM (X-ray 2.51A ) 4CCN (X-ray 2.23A ) 4CCO (X-ray 2.30A ) 4DIQ (X-ray 2.40A ) 4E4H (X-ray 2.28A ) 4Y33 (X-ray 2.70A ) 4Y3O (X-ray 2.20A ) 4Y4R (X-ray 3.30A ) |
| DBSNP | rs10144469 rs758109 rs34970526 rs3813563 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:14742713, ECO:0000269|PubMed:17308053}. Nucleus, nucleoplasm {ECO:0000269|PubMed:17308053}. Note=Granular part of nucleoli (PubMed:14742713). Nucleoplasm, nucleoplasmic foci, some of them associated with nucleoli (PubMed:14742713). {ECO:0000269|PubMed:14742713}. |
| Mouse PG classification | NA |
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